BP MONITOR WITH VESSELS’ FUNCTIONING ASSESSMENT

The project of creating a blood pressure (BP) tonometer with non-invasive assessment of vascular functions. Today, hundreds of millions of people around the world with various cardiovascular diseases are exposed to blood pressure (BP) measurement procedures in clinics and at home with BP tonometers of varying complexity and accuracy. First of all, regular measurement of BP is necessary for patients with arterial hypertension of various etiologies. However, the reasons for the development of arterial hypertension (hypotension), and the pathogenesis of the disease, as well as the risks of complications – all these also depends on the state of blood vessels: their tone, wall stiffness (presence of calcification), the functioning of the endothelium, etc. In clinics, such complex studies of blood vessels are expensive and time-consuming. There are no cheap and affordable devices on the market, especially for the home usage (except for the BP tonometers themselves). The project is aimed at solving the problem of an objective instrumental and rapid assessment of the state of blood vessels in patients with arterial hypertension and other diseases of the cardiovascular system without the use of expensive ultrasound, CT, and MRI methods. To this end, it is proposed to supplement the design of a conventional automated BP monitor with external optical sensors (probes) attached to the patient’s extremities, which, using optical flowmetry and photoplethysmography technologies, simultaneously with measuring the BP, can measure parameters for assessing the functioning of blood vessels: pulse wave velocity (PWV) for assessing a stiffness of arterial walls, perfusion to assess the baseline vascular tone, and several others. The idea of creating of such a tonometer is being worked out in this project. An application form for a patent of the Russian Federation No.2020131390 dated on 23.09.2020 was filed and submitted. The project is at the stage of research and development and the stage of seeking a grant funding for the research.

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